Overview
Resources
Sub-types
Other Names
Associated Disorders
Diagnosis
Causes
Treatments

Creutzfeldt-Jakob Disease is a rare prion brain disease that is fatal to humans. This disease is faster acting than most other kinds of dementia.

Creutzfeldt-Jakob Disease Sub-types

  • Sporadic Creutzfeldt-Jakob Disease,
  • Familial Creutzfeldt-Jakob Disease,
  • Acquired Creutzfeldt- Jakob Disease

Creutzfeldt-Jakob Disease Other Names

CJD

Creutzfeldt- Jakob Dementia

Creutzfeldt-Jakob Disease Dementia

Associated Disorders

Alzheimer’s and Dementia

Mad Cow Disease

Creutzfeldt- Jakob Disease is diagnosed with

  • EEG’s,
  • MRI,
  • Spinal tap,
  • Protein Misfolding cyclic amplification (PMCA)- which is a technique to identify misfolded proteins.

Creutzfeldt-Jakob Disease is caused by a prison protein that unfolds into a 3D shape which then gradually makes these protiens in the brain to change shape which damages the brain.

  • Medical procedures that insert growth hormone can cause it,
  • Meat infected with bovine Spongiform Encephalopathy (BVE) also known as Mad Cow Disease.
  • Many causes of Creutzfeldt-Jakob disease are genetic resulting from certain changes in the Chromosome 20 gene coding. Including a protein gene location “codon 129”
    • More than 50 variants in the prion protein gene have been identified which increase the likely hood of one developing this disease, according to ALZ.org

Creutzfeldt- Jakob Disease Treatments

No treatments at this time however some symptoms such as pain can be treated by doctors to lesson suffering of patients- Alz.org